Preheat your oven to 350°F (175°C).
In a mixing bowl, combine ground beef, garlic powder, onion powder, salt, and pepper.
Shape the beef mixture into small patties that are slightly larger than the slider buns.
Place the patties on a baking sheet lined with parchment paper.
Bake the patties in the preheated oven for about 15 minutes or until cooked to your desired doneness.
Remove from the oven and place a slice of cheese on top of each patty.
While the cheese melts, prepare the slider buns by cutting them horizontally in half.
Assemble the sliders by placing the cooked patties on the bottom half of the buns and adding your favorite toppings.
Top each slider with the other half of the bun and serve warm.
